Marvel Villains and Heroes often die and make a comeback. Characters have died and returned multiple times but for these Marvel villains, death was the end of their stories.
1. Barracuda: Frank Castle has faced Barracuda many times. He was introduced in PunisherMAX. He was The Punisher’s nemesis. Barracuda was supposed to be a one-off character. The Punisher murdered Barracuda, and he hasn’t been seen since.
2. Ultimate Magneto: Ultimate Magneto’s fate was different compared to his on-screen counterpart. As a Marvel Villain, 616 Magneto has evaded death a couple of times, but Cyclops killed Magneto permanently.
3. Bart Hamilton: A second Goblin reappeared in The Amazing Spider-Man #176-180 after Harry Osborne’s appearance. The second Goblin was Bart Hamilton. He was Harry’s hypnotherapist. Harry, as Goblin, faced him and killed him as well
4. Angelo Fortunato: Many Marvel Villains have been hosts to the Symbiote. One of the shortest ones was Angelo Fortunato. He was a young mafia brat. His father gifted him to the Symbiote in order to gain a favor. Spider-Man eventually killed him, never to be seen again.
5. Marco Scarlotti: Marco was the original Backlash and was a pain for Ironman. Ironman’s new sentient armor killed him. There have been other Whiplash villains but the original Scarlotti remains dead.