Acting Duos That Have Such Brilliant Chemistry The Movies Keep Casting Them Over & Over

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Hollywood is home to many well-known acting duos. But these acting duos have such epic chemistry that Hollywood keeps casting them over & over again. Some you knew but never paid enough notice. Some other famous acting duos you probably have never even heard of. nevertheless, they are iconic and everyone should appreciate them for making Hollywood a tad bit better, one movie at a time.


Winston Duke & Lupita Nyong’o

Acting Duos With Brilliant Chemistry
Jordan Peele’s Us

Both Winston Duke and Lupita Nyong’o are accomplished actors. But did you know they go way back together. Both of them are alumni of the prestigious Yale Drama School. It is no coincidence that the two African-American actors, who consider themselves pillars of a very small community in the film industry, keep being cast together. One of the only acting duos to have had back to back successes, Nyong’o and Duke were first seen together in Black Panther in 2018. They they starred again in Jordan Peele’s Us in 2019. Both were critical and commercial hits.

Benedict Cumberbatch & Martin Freeman

Acting Duos With Brilliant Chemistry

Many instantly recognize one of TV’s greatest acting duos from the hit TV series – Sherlock. Cumberbatch portrayed Sherlock Holmes while Martin Freeman portrayed Watson. But the two have also moved on to star in some epic blockbuster movies. The two were again seen in The Hobbit: The Desolation Of Smaug. Freeman played Bilbo the Hobbit while Cumberbatch played the titular dragon – Smaug. The two are also a part of the MCU.


Chris Evans & Scarlett Johansson

Acting Pairs With Brilliant Chemistry
The Nanny Diaries came way before the MCU

Before Evans became Captain America, he was a rom-com sweetheart who also starred in several YA movies. Scarlett Johansson came to the MCU much later in her career. Evans and Johansson are now known for their epic chemistry during Captain America; The Winter Soldier. But the two had already shared a screen before that MCU movie. Scarlett Johansson and Chris Evans played romantic interest of each other in the 2007 film – The Nanny Diaries.

Tessa Thompson & Chris Hemsworth

Acting Pairs With Brilliant Chemistry
Thor: Ragnarok

Tessa Thompson is a talented young actor who has still a long way to go before she achieves the bright future and super-stardom she truly deserves in the industry. Chris Hemsworth is already a mega-star of Hollywood. The Creed actor and Extraction actor pair very well together. They have both starred in Thor 3, where Tessa played Valkyrie and Chris played the iconic Thor. They were again seen as leads in Men In Black: International. Although the movie failed to raise eyebrows, the Tessa Thompson-Chris Hemsworth chemistry was appreciated.

Jake Gyllenhaal & Anne Hathaway

Acting Duos With Amazing Chemistry
Love & Other Drugs

They just may be one of the cutest acting duos to ever exist in Hollywood. But seldom does the chemistry between them get acknowledged. Gyllenhaal and Hathaway have done multiple movies together. They were there in Brokeback Mountain. The two also played leads in Love & Other Drugs. The viewers love how Anne and Jake bring out the best in each other when sharing the same frame.


Samuel L. Jackson & Bruce Willis

Acting Pairs With Epic Chemistry

One of them has become one of the biggest stars in Hollywood. The other has fallen from grace pretty hard. We will let you which one’s which. The Samuel L Jackson-Bruce Willis pair is one of the most legendary action-genre acting duos though. They were there in Pulp Fiction. They were also there in Unbreakable, Die Hard With A Vengeance, and Glass. Samuel L Jackson’s over the top humor complements well with Bruce Willis’ serious and stoic acting.

Kate Winslet & Leonardo DiCaprio

Acting Duos With Insane Chemistry
Revolutionary Road & Titanic

We are not even going to explain how perfect these two actors‘ chemistry is on screen. After starring in Titanic, the two also starred in another tragic movie – Revolutionary Road. The two, when together, were brilliant then. They are brilliant now as well.

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Written by Bibhu Prasad Panda

Articles Published: 1230

With a Bachelor's in Engineering and a Master's in Marketing and Operations, Bibhu found a love for writing, working for many different websites. He joined FandomWire in July 2020 and worked his way to his current position of Content Strategist. Bibhu has been involved in operating and managing FandomWire's team of writers, diversifying into varied, exotic fields of pop culture.